Article
Relationships between polymorphisms of the human serum paraoxonase gene and insulin sensitivity in Japanese patients with type 2 diabetes.
Diabetes research and clinical practice - 1 May 2003
Ikeda Yukio, Suehiro Tadashi, Ohsaki Fumiaki, Arii Kaoru, Kumon Yoshitaka, Hashimoto Kozo
Abstract excerpt
Human serum paraoxonase (PON1), which is associated with HDL, is an esterase and has been shown to reduce the susceptibility of LDL to lipid peroxidation. The objective of the study was to determine whether genetic polymorphisms of the PON1 gene are associated with insulin sensitivity. Forty-eight Japanese patients with type 2 diabetes were recruited, and euglycemic hyperinsulinemic clamp was performed to assess...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.