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Article

MED28 Regulates Epithelial-Mesenchymal Transition Through NFκB in Human Breast Cancer Cells.

Journal of cellular physiology - 1 Jun 2017

Huang Chun-Yin, Hsieh Nien-Tsu, Li Chun-I, Weng Yu-Ting, Liu Hsiao-Sheng, Lee Ming-Fen

Abstract excerpt

MED28, a mammalian Mediator subunit, was found highly expressed in several types of malignancy, including breast cancer. Recently, we have identified a role of MED28 in regulating both cell growth and migration in human breast cancer cells. In epithelium-derived solid tumor, migration and invasion are preceded by the progression of epithelial-mesenchymal transition (EMT) which calls for downregulation of...

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Source

Identifiers

PMID: 27662245
DOI: 10.1002/jcp.25610

Genes

MED28
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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