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Article

Altered metabolite levels in cancer: implications for tumour biology and cancer therapy.

Nature reviews. Cancer - 1 Nov 2016

Sullivan Lucas B, Gui Dan Y, Vander Heiden Matthew G

Abstract excerpt

Altered cell metabolism is a characteristic feature of many cancers. Aside from well-described changes in nutrient consumption and waste excretion, altered cancer cell metabolism also results in changes to intracellular metabolite concentrations. Increased levels of metabolites that result directly from genetic mutations and cancer-associated modifications in protein expression can promote cancer initiation and...

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PMID: 27658530
DOI: 10.1038/nrc.2016.85

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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