Article
Alterations of metabolic genes and metabolites in cancer.
Seminars in cell & developmental biology - 1 Jun 2012
Oermann Eric K, Wu Jing, Guan Kun-Liang, Xiong Yue
Abstract excerpt
Altered metabolic regulation has long been observed in human cancer and broadly used in the clinic for tumor detection. Two recent findings--the direct regulation of metabolic enzymes by frequently mutated cancer genes and frequent mutations of several metabolic enzymes themselves in cancer--have...
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