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Article

Regulation of immune cell metabolism by cancer cell oncogenic mutations.

International journal of cancer - 15 Jul 2020

Madi Alaa, Cui Guoliang

Abstract excerpt

In noncancerous tissues, neighboring cells coexist in metabolic harmony. This metabolic harmony is disrupted in cancerous tissues, often accompanied by genetic mutations. Tumor cells fundamentally change the metabolite profiles in the tumor microenvironment to favor their own growth. In this review, we will discuss several examples in which genetic mutations reprogram tumor cell metabolic pathways, leading to the...

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Identifiers

PMID: 31994718
DOI: 10.1002/ijc.32888

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