Article
MAVS is not a Likely Susceptibility Locus for Addison's Disease and Type 1 Diabetes.
Archivum immunologiae et therapiae experimentalis - 1 Jun 2017
Zurawek Magdalena, Fichna Marta, Kazimierska Marta, Fichna Piotr, Dzikiewicz-Krawczyk Agnieszka, Przybylski Grzegorz, Ruchala Marek, Nowak Jerzy
Abstract excerpt
Mitochondrial antiviral signaling (MAVS) protein is an intracellular adaptor molecule, downstream of viral sensors, retinoid acid-inducible gene I (RIG-I)-like receptors (RLRs). Impaired antiviral cell signaling might contribute to autoimmunity. Studies have recently shown variations in genes encoding RLRs as risk factors for autoimmune diseases. We investigated whether MAVS coding polymorphisms are associated...
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