Article
Programmed death ligand 1 (PD-L1) gene variants contribute to autoimmune Addison's disease and Graves' disease susceptibility.
The Journal of clinical endocrinology and metabolism - 1 Dec 2009
Mitchell Anna L, Cordell Heather J, Soemedi Rachel, Owen Kate, Skinningsrud Beate, Wolff Anette Bøe, Ericksen Martina, Undlien Dag, Husebye Eystein, Pearce Simon H S
Abstract excerpt
CONTEXT: Despite much investigation, a substantial amount of the genetic susceptibility to autoimmune diseases remains unaccounted for. Recently, a single-nucleotide polymorphism (SNP) in the programmed death ligand 1 (PD-L1) gene has been associated with Graves' disease (GD) in a Japanese patient cohort. Our aim was to determine whether variants in PD-L1 are also associated with autoimmune Addison's disease...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.