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Article

A coding variant in NLRP1 is associated with autoimmune Addison's disease.

Human immunology - 1 May 2010

Zurawek Magdalena, Fichna Marta, Januszkiewicz-Lewandowska Danuta, Gryczyńska Maria, Fichna Piotr, Nowak Jerzy

Abstract excerpt

Autoimmune Addison's disease (AAD) is a complex disorder with several susceptibility loci. Variations in the NLRP1 (previously, NALP1) gene have recently been reported to confer risk for vitiligo and associated autoimmune conditions. We hypothesized that polymorphisms in this gene may affect susceptibility to AAD. The aim of this study was to analyze the associations of six NLRP1 single-nucleotide polymorphisms...

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Topics

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Share to Adaptor Proteins, Signal Transducing
Share to Addison Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Apoptosis Regulatory Proteins

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Share to Polymorphism, Restriction Fragment Length

Share to Polymorphism, Single Nucleotide

Share to Polymorphism, Single-Stranded Conformational

Source

Identifiers

PMID: 20152874
DOI: 10.1016/j.humimm.2010.02.004

Genes

NLRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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