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Article

Validating genetic markers of response to recombinant human growth hormone in children with growth hormone deficiency and Turner syndrome: the PREDICT validation study.

European journal of endocrinology - 1 Dec 2016

Stevens Adam, Murray Philip, Wojcik Jerome, Raelson John, Koledova Ekaterina, Chatelain Pierre, Clayton Peter

Abstract excerpt

OBJECTIVE: Single-nucleotide polymorphisms (SNPs) associated with the response to recombinant human growth hormone (r-hGH) have previously been identified in growth hormone deficiency (GHD) and Turner syndrome (TS) children in the PREDICT long-term follow-up (LTFU) study (Nbib699855). Here, we describe the PREDICT validation (VAL) study (Nbib1419249), which aimed to confirm these genetic associations. DESIGN AND...

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Source

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Identifiers

PMID: 27651465
DOI: 10.1530/EJE-16-0357
PMCID: PMC5097129

Genes

ESR1
FOS
GHRHR
GRB10
IGF2
IGFBP3
INPPL1
PTPN1
SOS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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