Article

Gene expression signatures predict response to therapy with growth hormone

2019-05-17

Abstract excerpt

Recombinant human growth hormone (r-hGH) is used as a therapeutic agent for disorders of growth including growth hormone deficiency (GHD) and Turner syndrome (TS). Treatment is costly and current methods to model response can only account for up to 60% of the variance. The aim of this work was to take a novel genomic approach to growth prediction. GHD (n=71) and TS patients (n=43) were recruited in a study on the...

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Literature Corpus work: be8cc805-f6de-545f-844c-5a8fb2af4b0a
DOI: 10.1101/637892

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