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Article

A pharmacogenomic approach to the treatment of children with GH deficiency or Turner syndrome.

European journal of endocrinology - 1 Sept 2013

Clayton P, Chatelain P, Tatò L, Yoo H W, Ambler G R, Belgorosky A, Quinteiro S, Deal C, Stevens A, Raelson J, Croteau P, Destenaves B, Olivier C

Abstract excerpt

OBJECTIVE: Individual sensitivity to recombinant human GH (r-hGH) is variable. Identification of genetic factors contributing to this variability has potential use for individualization of treatment. The objective of this study was to identify genetic markers and gene expression profiles associated with growth response on r-hGH therapy in treatment-naïve, prepubertal children with GH deficiency (GHD) or Turner...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23761422
DOI: 10.1530/EJE-13-0069
PMCID: PMC3731924

Genes

AKT1
GRB10
KRAS
LHX4
MYOD1
PTPN1
SOS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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