Article
Convergent Effects of Resveratrol and PYK2 on Prostate Cells.
International journal of molecular sciences - 13 Sept 2016
Conte Andrea, Kisslinger Annamaria, Procaccini Claudio, Paladino Simona, Oliviero Olimpia, de Amicis Francesca, Faicchia Deriggio, Fasano Dominga, Caputo Marilena, Matarese Giuseppe, Pierantoni Giovanna Maria, Tramontano Donatella
Abstract excerpt
Resveratrol, a dietary polyphenol, is under consideration as chemopreventive and chemotherapeutic agent for several diseases, including cancer. However, its mechanisms of action and its effects on non-tumor cells, fundamental to understand its real efficacy as chemopreventive agent, remain largely unknown. Proline-rich tyrosine kinase 2 (PYK2), a non-receptor tyrosine kinase acting as signaling mediator of...
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