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Article

Structural basis for norovirus neutralization by an HBGA blocking human IgA antibody.

Proceedings of the National Academy of Sciences of the United States of America - 4 Oct 2016

Shanker Sreejesh, Czakó Rita, Sapparapu Gopal, Alvarado Gabriela, Viskovska Maria, Sankaran Banumathi, Atmar Robert L, Crowe James E, Estes Mary K, Prasad B V Venkataram

Abstract excerpt

Human noroviruses (HuNoVs) cause sporadic and epidemic gastroenteritis worldwide. They are classified into two major genogroups (GI and GII), with each genogroup further divided into multiple genotypes. Susceptibility to these viruses is influenced by genetically determined histo-blood group antigen (HBGA) expression. HBGAs function as cell attachment factors by binding to a surface-exposed region in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27647885
DOI: 10.1073/pnas.1609990113
PMCID: PMC5056091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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