Article
Characterization of a Novel Conformational GII.4 Norovirus Epitope: Implications for Norovirus-Host Interactions.
Journal of virology - 1 Sept 2016
Carmona-Vicente Noelia, Vila-Vicent Susana, Allen David, Gozalbo-Rovira Roberto, Iturriza-Gómara Miren, Buesa Javier, Rodríguez-Díaz Jesús
Abstract excerpt
UNLABELLED: Human noroviruses (NoVs) are the main etiological agents of acute gastroenteritis worldwide. While NoVs are highly diverse (more than 30 genotypes have been detected in humans), during the last 40 years most outbreaks and epidemics have been caused by GII.4 genotype strains, raising questions about their persistence in the population. Among other potential explanations, immune evasion is considered to...
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