Article
Structural analysis of determinants of histo-blood group antigen binding specificity in genogroup I noroviruses.
Journal of virology - 1 Jun 2014
Shanker Sreejesh, Czako Rita, Sankaran Banumathi, Atmar Robert L, Estes Mary K, Prasad B V Venkataram
Abstract excerpt
UNLABELLED: Human noroviruses (NoVs) cause acute epidemic gastroenteritis. Susceptibility to the majority of NoV infections is determined by genetically controlled secretor-dependent expression of histo-blood group antigens (HBGAs), which are also critical for NoV attachment to host cells. Human NoVs are classified into two major genogroups (genogroup I [GI] and GII), with each genogroup further divided into...
Topics
- Amino Acid Sequence
- Antigens, Viral
- Base Sequence
- Blotting, Western
- Crystallography
- Dimerization
- Enzyme-Linked Immunosorbent Assay
- Epitopes
- Genotype
- Humans
- Models, Molecular
- Molecular Sequence Data
- Norovirus