Article
[Characterization of mutational pattern in patients with Ph negative myeloproliferative neoplasms].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 8 Sept 2016
Xing F, Lin Y N, Sun Q, Qin L, Jia Y J, Zhang D L, Ru K
Abstract excerpt
OBJECTIVE: To characterize the molecular profile in patients with Ph negative myeloproliferative neoplasms (MPN) by exploring 49 gene mutations. METHODS: Targeted gene sequencing were performed to analyze 49 MPN-associated genes in 51 patients with Ph negative MPN, of which CARL (exon 9), NPM1 (exon 12) and CEBPA (TAD, BZIP domains) were investigated by using Sanger sequencing simultaneously, while FLT3-ITD was...
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