Article
[Clinical significance of JAK2、CALR and MPL gene mutations in 1 648 Philadelphia chromosome negative myeloproliferative neoplasms patients from a single center].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 14 Apr 2017
Li M Y, Chao H Y, Sun A N, Qiu H Y, Jin Z M, Tang X W, Han Y, Fu C C, Chen S N, Wu D P
Abstract excerpt
Objective: To explore the prevalences of JAK2, CALR and MPL gene mutations and the mutation types in patients with Philadelphia chromosome negative myeloproliferative neoplasms (MPNs) , and to compare their clinical characteristics of different mutation types with each other and mutation negative group. Methods: The mutations of JAK2 V617F, JAK2 gene at exon 12, CALR gene at exon 9 and MPL gene at exon 10 in 1...
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