Article
Clinical laboratory characteristics and gene mutation spectrum of Ph-negative MPN patients with atypical variants of JAK2, MPL, or CALR.
Cancer medicine - 1 Apr 2024
Wang Zhanlong, Tian Xin, Ma Jinyu, Zhang Yuhui, Ta Wenru, Duan Yifan, Li Fengli, Zhang Hong, Chen Long, Yang Shaobin, Liu Enbin, Lin Yani, Yuan Weiping, Ru Kun, Bai Jie
Abstract excerpt
OBJECTIVE: To evaluate the incidence, clinical laboratory characteristics, and gene mutation spectrum of Ph-negative MPN patients with atypical variants of JAK2, MPL, or CALR. METHODS: We collected a total of 359 Ph-negative MPN patients with classical mutations in driver genes JAK2, MPL, or CALR, and divided them into two groups based on whether they had additional atypical variants of driver genes JAK2, MPL, or...
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