Article
Prevalence and clinicopathological features of driver gene mutations profile in BCR:ABL1 negative classical myeloproliferative neoplasm-A single-center study from North India.
Indian journal of pathology & microbiology - 1 Oct 2024
Rahman Khaliqur, Biswas Seema, Sharma Akhilesh, Gupta Kusum, Chandra Dinesh, Singh Manish K, Gupta Ruchi, Mishra Ashish, Kumar Sanjeev, Gupta Anshul, Hasan Faheema, Nityanand Soniya, Kahsyap Rajesh
Abstract excerpt
BACKGROUND: Recurrent somatic mutations in the JAK2 , CALR , and the MPL genes are noted in BCR:ABL1 negative classic myeloproliferative neoplasms (MPN) that includes polycythemia vera (PV), essential thrombocytosis (ET), and primary myelofibrosis (PMF). MATERIALS AND METHODS: Mutation profile and clinical features of MPN cases diagnosed at a tertiary care center in North India are being described. JAK2V617F...
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