Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A new effLuc/Kate dual reporter allele for tumor imaging in mice.

Disease models & mechanisms - 1 Jan 2025

Bakiri Latifa, Tichet Mélanie, Marques Carolina, Thomsen Martin K, Allen Elizabeth A, Stolzlechner Stefanie, Cheng Ke, Matsuoka Kazuhiko, Squatrito Massimo, Hanahan Douglas, Wagner Erwin F

Abstract excerpt

Genetically engineered mouse models (GEMMs) are instrumental for modelling local and systemic features of complex diseases, such as cancer. Non-invasive, longitudinal cell detection and monitoring in tumors, metastases and/or the micro-environment is paramount to achieve a better spatiotemporal understanding of cancer progression and to evaluate therapies in preclinical studies. Bioluminescent and fluorescent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Genes, Reporter

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Integrases

Share to Luminescent Measurements

Share to Mice, Transgenic

Share to Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 39745082
DOI: 10.1242/dmm.052130
PMCID: PMC11789939

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A new effLuc/Kate dual reporter allele for tumor imaging in mice.PMID 39745082Read ↗

Versatile and enhanced tumour modelling in mice via somatic cell transduction.Semantic proximity Read ↗

Multi-scale in vivo imaging of tumour development using a germline conditional triple-reporter systemSemantic proximity Read ↗

Genetically engineered knock-in and conditional knock-in mouse models of cancer.Semantic proximity Read ↗

Novel mouse reporter models for the detection of genome editing events in vivoSemantic proximity Read ↗

iFlpMosaics enable the multispectral barcoding and high-throughput comparative analysis of mutant and wildtype cellsSemantic proximity Read ↗

EyaHOST, a modular genetic system for investigation of intercellular and tumor-host interactions <i>in Drosophila melanogaster</i>Semantic proximity Read ↗

Temporally and spatially controlled expression of transgenes in embryonic and adult tissues.Semantic proximity Read ↗

Novel transgenic mice with Cre-dependent co-expression of GFP and human ACE2: a safe tool for study of COVID-19 pathogenesisSemantic proximity Read ↗

CRISPR-SONIC: targeted somatic oncogene knock-in enables rapid in vivo cancer modelingSemantic proximity Read ↗

The invertor knock-in conditional chromosomal translocation mimic.Semantic proximity Read ↗

Generation and applications of MADM-based mouse genetic mosaic system.Semantic proximity Read ↗

Enhanced AkaLuc Bioluminescence Imaging for Longitudinal Intravital Monitoring of Minimal Residual Disease in a Murine Model of Triple-negative Breast CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.