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Article

Cre reconstitution allows for DNA recombination selectively in dual-marker-expressing cells in transgenic mice.

Nucleic acids research - 1 Jan 2007

Xu Yanwen, Xu Gang, Liu Bindong, Gu Guoqiang

Abstract excerpt

Cre/LoxP-based DNA recombination has been used to introduce desired DNA rearrangements in various organisms, having for example, greatly assisted genetic analyses in mice. For most applications, single gene promoters are used to drive Cre production for conditional gene activation/inactivation or lineage-tracing experiments. Such a manipulation introduces Cre in all cells in which the utilized promoter is active....

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Identifiers

PMID: 17893102
DOI: 10.1093/nar/gkm559
PMCID: PMC2095822

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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