Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

AXIN1 Expression and Localization in Meningiomas and Association to Changes of APC and E-cadherin.

Anticancer research - 1 Sept 2016

Pećina-Šlaus Nives, Kafka Anja, Vladušić Tomislav, Pećina Hrvoje Ivan, Hrašćan Reno

Abstract excerpt

BACKGROUND/AIM: Tumor suppressor gene AXIN1 is an inhibitor of Wnt signaling pathway. It down-regulates the pathway's main signaling effector molecule, beta-catenin, in an AXIN-based destruction complex. In the present study we investigated the involvement of AXIN1 in intracranial meningioma. MATERIALS AND METHODS: Loss of heterozygosity and microsatellite instability analyses were performed. The consequences of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenomatous Polyposis Coli Protein
Share to Axin Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to beta Catenin

Share to Cadherins

Share to Cytoplasm

Share to Loss of Heterozygosity

Share to Meningioma

Share to Wnt Signaling Pathway

Source

Identifiers

PMID: 27630299
DOI: 10.21873/anticanres.11007

Genes

AXIN1
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

AXIN1 Expression and Localization in Meningiomas and Association to Changes of APC and E-cadherin.PMID 27630299Read ↗

The links between axin and carcinogenesisSemantic proximity Read ↗

Tumor formation by genetic mutations in the components of the Wnt signaling pathway.Semantic proximity Read ↗

Detection of a novel alteration of the Axin gene in various pediatric neoplasms.Semantic proximity Read ↗

Reduced expression of Axin correlates with tumour progression of oesophageal squamous cell carcinoma.Semantic proximity Read ↗

Aberrant nuclear localization of β-catenin without genetic alterations in β-catenin or Axin genes in esophageal cancerSemantic proximity Read ↗

AXIN1 mutations but not deletions in cerebellar medulloblastomas.Semantic proximity Read ↗

Mutations of the APC, beta-catenin, and axin 1 genes and cytoplasmic accumulation of beta-catenin in oral squamous cell carcinoma.Semantic proximity Read ↗

Mutations of the Wnt antagonist AXIN2 (Conductin) result in TCF-dependent transcription in medulloblastomas.Semantic proximity Read ↗

AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1.Semantic proximity Read ↗

Preserved Axin expression is associated with an aggressive phenotype in invasive breast carcinomas.Semantic proximity Read ↗

Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3βSemantic proximity Read ↗

Mutation analysis of CTNNB1 (beta-catenin) and AXIN1, the components of Wnt pathway, in cervical carcinomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.