Article
Reduced expression of Axin correlates with tumour progression of oesophageal squamous cell carcinoma.
British journal of cancer - 2 Jun 2003
Nakajima M, Fukuchi M, Miyazaki T, Masuda N, Kato H, Kuwano H
Abstract excerpt
Axin is a negative regulator of the Wnt signalling pathway, and genetic alterations of AXIN1 have been suggested to be an important factor of carcinogenesis in some tumours. The objective of this study was to clarify the clinicopathologic and prognostic significance of Axin in oesophageal squamous cell carcinoma (SCC). Immunohistochemical staining for Axin was performed on surgical specimens obtained from 81...
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