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Article

Carriers of a VEGFA enhancer polymorphism selectively binding CHOP/DDIT3 are predisposed to increased circulating levels of thyroid-stimulating hormone.

Journal of medical genetics - 1 Mar 2017

Ahluwalia Tarunveer Singh, Troelsen Jesper Thorvald, Balslev-Harder Marie, Bork-Jensen Jette, Thuesen Betina Heinsbæk, Cerqueira Charlotte, Linneberg Allan, Grarup Niels, Pedersen Oluf, Hansen Torben, Dalgaard Louise Torp

Abstract excerpt

BACKGROUND: Levels of serum thyroid-stimulating hormone (TSH) indicate thyroid function, because thyroid hormone negatively controls TSH release. Genetic variants in the vascular endothelial growth factor A (VEGFA) gene are associated with TSH levels. The aim of this study was to characterise the association of VEGFA variants with TSH in a Danish cohort and to identify and characterise functional variants....

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Source

Identifiers

PMID: 27627987
DOI: 10.1136/jmedgenet-2016-104084

Genes

VEGFA
DDIT3
EBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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