Article
Vascular endothelial growth factor gene polymorphisms in thyroid cancer.
The Journal of endocrinology - 1 Nov 2007
Hsiao Pi-Jung, Lu Ming-Ying, Chiang Feng-Yu, Shin Shyi-Jang, Tai Yu-Da, Juo Suh-Hang Hank
Abstract excerpt
Vascular endothelial growth factor (VEGF) is a potent stimulator for angiogenesis. It has been implicated in growth and metastasis of thyroid cancer. Three functional single nucleotide polymorphisms (SNPs) of VEGF (-2578C/A, -634G/C, and +936C/T) are known to be related with VEGF expression. We conducted a case-control study to evaluate the genetic effects of these three functional SNPs on the development of...
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