Article
TumorNext: A comprehensive tumor profiling assay that incorporates high resolution copy number analysis and germline status to improve testing accuracy.
Oncotarget - 18 Oct 2016
Gray Phillip N, Vuong Huy, Tsai Pei, Lu Hsaio-Mei, Mu Wenbo, Hsuan Vickie, Hoo Jayne, Shah Swati, Uyeda Lisa, Fox Susanne, Patel Harshil, Janicek Mike, Brown Sandra, Dobrea Lavinia, Wagman Lawrence, Plimack Elizabeth, Mehra Ranee, Golemis Erica A, Bilusic Marijo, Zibelman Matthew, Elliott Aaron
Abstract excerpt
The development of targeted therapies for both germline and somatic DNA mutations has increased the need for molecular profiling assays to determine the mutational status of specific genes. Moreover, the potential of off-label prescription of targeted therapies favors classifying tumors based on DNA alterations rather than traditional tissue pathology. Here we describe the analytical validation of a custom...
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