Article
Validation of OncoPanel: A Targeted Next-Generation Sequencing Assay for the Detection of Somatic Variants in Cancer.
Archives of pathology & laboratory medicine - 1 Jun 2017
Garcia Elizabeth P, Minkovsky Alissa, Jia Yonghui, Ducar Matthew D, Shivdasani Priyanka, Gong Xin, Ligon Azra H, Sholl Lynette M, Kuo Frank C, MacConaill Laura E, Lindeman Neal I, Dong Fei
Abstract excerpt
CONTEXT: - The analysis of somatic mutations across multiple genes in cancer specimens may be used to aid clinical decision making. The analytical validation of targeted next-generation sequencing panels is important to assess accuracy and limitations. OBJECTIVE: - To report the development and validation of OncoPanel, a custom targeted next-generation sequencing assay for cancer. DESIGN: - OncoPanel was designed...
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