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ClinBioNGS: A Clinical Bioinformatics Pipeline for Integrated Analysis of Somatic Next-Generation Sequencing Cancer Panels.

JCO clinical cancer informatics - 1 Jan 2026

Marín Raúl, Alay Ania, Ajenjo-Bauza Maria, Hijazo-Pechero Sara, Montironi Carla, Hernández-Illán Eva, Jares Pedro, Azuara Daniel, Varela Mar, Vidal August, Puig-Butillé Joan Anton, Lázaro Conxi, Moreno Víctor, Cordero David, Nadal Ernest, Solé Xavier

Abstract excerpt

PURPOSE: Somatic next-generation sequencing (NGS) panels are widely used in precision oncology to detect clinically actionable genomic alterations. However, interpreting diverse DNA and RNA alterations remains challenging because of the complexity of tumor-only data and the limitations of current pipelines, which are often proprietary, noncustomizable, or lack visual reports to support clinical interpretation. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41505665
DOI: 10.1200/CCI-25-00221

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