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Clinical Tumor Sequencing: Opportunities and Challenges for Precision Cancer Medicine

1 May 2015

Abstract excerpt

Advances in tumor genome sequencing have enabled discovery of actionable alterations leading to novel therapies. Currently, there are approved targeted therapies across various tumors that can be matched to genomic alterations, such as point mutations, gene amplification, and translocations. Tools to detect these genomic alterations have emerged as a result of decreasing costs and improved throughput enabled by...

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PMID: 25993170
DOI: 10.14694/edbook_am.2015.35.e175

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