Article
Clinical Outcomes of TP53 Mutations in Cancers.
Cold Spring Harbor perspectives in medicine - 1 Sept 2016
Robles Ana I, Jen Jin, Harris Curtis C
Abstract excerpt
High-throughput sequencing of cancer genomes is increasingly becoming an essential tool of clinical oncology that facilitates target identification and targeted therapy within the context of precision medicine. The cumulative profiles of somatic mutations in cancer yielded by comprehensive molecular studies also constitute a fingerprint of historical exposures to exogenous and endogenous mutagens, providing...
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