Article
Somatic mutations in cancer prognosis and prediction: lessons from TP53 and EGFR genes.
Current opinion in oncology - 1 Jan 2011
Olivier Magali, Taniere Philippe
Abstract excerpt
PURPOSE OF REVIEW: We used two examples of genes, TP53 and EGFR, which are somatically altered by intragenic mutations in common cancer types to illustrate how somatic mutations have followed very different routes to clinical applications. RECENT FINDINGS: TP53 somatic mutations are frequent in m...
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