Article
Ultrasonic Assessment of Myocardial Microstructure in Hypertrophic Cardiomyopathy Sarcomere Mutation Carriers With and Without Left Ventricular Hypertrophy.
Circulation. Heart failure - 1 Sept 2016
Hiremath Pranoti, Lawler Patrick R, Ho Jennifer E, Correia Andrew W, Abbasi Siddique A, Kwong Raymond Y, Jerosch-Herold Michael, Ho Carolyn Y, Cheng Susan
Abstract excerpt
BACKGROUND: The noninvasive assessment of altered myocardium in patients with genetic mutations that are associated with hypertrophic cardiomyopathy (HCM) remains challenging. In this pilot study, we evaluated whether a novel echocardiography-based assessment of myocardial microstructure, the signal intensity coefficient (SIC), could detect tissue-level alterations in HCM sarcomere mutation carriers with and...
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