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Article

Fibrosis in Hypertrophic Cardiomyopathy Patients With and Without Sarcomere Gene Mutations.

Heart, lung & circulation - 1 Oct 2021

Vullaganti Sirish, Levine Jonathan, Raiker Nisha, Syed Amer Ahmed, Collins Jeremy D, Carr James C, Bonow Robert O, Choudhury Lubna

Abstract excerpt

BACKGROUND: Patients with hypertrophic cardiomyopathy (HCM) and an identified sarcomere mutation have worse outcomes than those without though the underlying mechanism is incompletely understood. The presence of replacement fibrosis measured by late gadolinium enhancement (LGE) and diffuse fibrosis measured by extracellular volume (ECV) using cardiac magnetic resonance imaging (CMR) are associated with...

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Source

Identifiers

PMID: 34023176
DOI: 10.1016/j.hlc.2021.04.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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