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Article

Effect of sarcomere and mitochondria-related mutations on myocardial fibrosis in patients with hypertrophic cardiomyopathy.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance - 4 Mar 2021

Chung Hyemoon, Kim Yoonjung, Park Chul-Hwan, Kim Jong-Youn, Min Pil-Ki, Yoon Young Won, Kim Tae Hoon, Lee Byoung Kwon, Hong Bum-Kee, Rim Se-Joong, Kwon Hyuck Moon, Lee Kyung-A, Choi Eui-Young

Abstract excerpt

BACKGROUND: Myocardial fibrosis is an important prognostic factor in hypertrophic cardiomyopathy (HCM). However, the contribution from a wide spectrum of genetic mutations has not been well defined. We sought to investigate effect of sarcomere and mitochondria-related mutations on myocardial fibrosis in HCM. METHODS: In 133 HCM patients, comprehensive genetic analysis was performed in 82 nuclear DNA (33...

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Share to Cardiomyopathy, Hypertrophic
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Echocardiography, Doppler

Share to Fibrosis

Share to Magnetic Resonance Imaging, Cine

Share to Mitochondria

Share to Myocardium

Share to Sarcomeres

Source

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Identifiers

PMID: 33658040
DOI: 10.1186/s12968-021-00718-3
PMCID: PMC7931545

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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