Article
T1 measurements identify extracellular volume expansion in hypertrophic cardiomyopathy sarcomere mutation carriers with and without left ventricular hypertrophy.
Circulation. Cardiovascular imaging - 1 May 2013
Ho Carolyn Y, Abbasi Siddique A, Neilan Tomas G, Shah Ravi V, Chen Yucheng, Heydari Bobak, Cirino Allison L, Lakdawala Neal K, Orav E John, González Arantxa, López Begoña, Díez Javier, Jerosch-Herold Michael, Kwong Raymond Y
Abstract excerpt
BACKGROUND: Myocardial fibrosis is a hallmark of hypertrophic cardiomyopathy (HCM) and a potential substrate for arrhythmias and heart failure. Sarcomere mutations seem to induce profibrotic changes before left ventricular hypertrophy (LVH) develops. To further evaluate these processes, we used cardiac magnetic resonance with T1 measurements on a genotyped HCM population to quantify myocardial extracellular...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.