Article
A comprehensive evaluation of myocardial fibrosis in hypertrophic cardiomyopathy with cardiac magnetic resonance imaging: linking genotype with fibrotic phenotype.
European heart journal. Cardiovascular Imaging - 1 Oct 2014
Ellims Andris H, Iles Leah M, Ling Liang-han, Chong Belinda, Macciocca Ivan, Slavin Glenn S, Hare James L, Kaye David M, Marasco Silvana F, McLean Catriona A, James Paul A, du Sart Desirée, Taylor Andrew J
Abstract excerpt
AIMS: In hypertrophic cardiomyopathy (HCM), attempts to associate genotype with phenotype have largely been unsuccessful. More recently, cardiac magnetic resonance (CMR) imaging has enhanced myocardial fibrosis characterization, while next-generation sequencing (NGS) can identify pathogenic HCM mutations. We used CMR and NGS to explore the link between genotype and fibrotic phenotype in HCM. METHODS AND RESULTS:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.