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Article

microRNA Expression during Trophectoderm Specification

2 Jul 2009

Abstract excerpt

BACKGROUND: Segregation of the trophectoderm from the inner cell mass of the embryo represents the first cell-fate decision of mammalian development. Transcription factors essential for specifying trophectoderm have been identified, but the role of microRNAs (miRNAs) in modulating this fate-choice has been largely unexplored. We have compared miRNA expression in embryonic stem cell (ESC)-derived trophectoderm and...

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PMID: 19582159
DOI: 10.1371/journal.pone.0006143

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