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Article

Identification of microRNAs and microRNA targets in Xenopus gastrulae: The role of miR-26 in the regulation of Smad1.

Developmental biology - 1 Jan 2016

Liu Chen, Lou Chih-Hong, Shah Vrutant, Ritter Ruth, Talley Julia, Soibam Benjamin, Benham Ashley, Zhu Huifeng, Perez Eloy, Shieh Yi-Er, Gunaratne Preethi H, Sater Amy K

Abstract excerpt

MicroRNAs (miRNAs) are known to play diverse roles in the regulation of vertebrate development. To investigate miRNA-target mRNA relationships in embryonic development, we have carried out small-RNA sequencing to identify miRNAs expressed in the early gastrula of Xenopus laevis. We identify a total of 180 miRNAs, and we have identified the locations of the miRNA precursor sequences in the X. laevis genome. Of...

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Identifiers

PMID: 26548531
DOI: 10.1016/j.ydbio.2015.11.005

Genes

BMP4

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