Article

ArfGAP1 regulates the endosomal sorting of guidance receptors to promote directed collective cell migration in vivo

2022-09-13

Abstract excerpt

<h4>ABSTRACT</h4> Chemotaxis drives diverse migrations important for development and involved in diseases, including cancer progression. Using border cells in the Drosophila egg chamber as a model for collective cell migration, we characterized the role of ArfGAP1 in regulating chemotaxis during this process. We found that ArfGAP1 is required for the maintenance of receptor tyrosine kinases, the guidance receptor...

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Literature Corpus work: 6d454599-2425-5bfe-9bb0-24752350c7fa
DOI: 10.1101/2022.09.13.507825

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