Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing.

Scientific reports - 12 Sept 2016

Ferreira Pedro G, Oti Martin, Barann Matthias, Wieland Thomas, Ezquina Suzana, Friedländer Marc R, Rivas Manuel A, Esteve-Codina Anna, Rosenstiel Philip, Strom Tim M, Lappalainen Tuuli, Guigó Roderic, Sammeth Michael

Abstract excerpt

Recent advances in the cost-efficiency of sequencing technologies enabled the combined DNA- and RNA-sequencing of human individuals at the population-scale, making genome-wide investigations of the inter-individual genetic impact on gene expression viable. Employing mRNA-sequencing data from the Geuvadis Project and genome sequencing data from the 1000 Genomes Project we show that the computational analysis of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Exons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to Introns

Share to Polyadenylation

Share to RNA Editing

Share to RNA Splice Sites

Share to Sequence Analysis, RNA

Source

Open in PubMed Open full text

Identifiers

PMID: 27617755
DOI: 10.1038/srep32406
PMCID: PMC5019111

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing.PMID 27617755Read ↗

Context-dependent robustness to 5' splice site polymorphisms in human populations.Semantic proximity Read ↗

The Expanding Landscape of Alternative Splicing Variation in Human Populations.Semantic proximity Read ↗

Complex Selection on Human Polyadenylation Signals Revealed by Polymorphism and Divergence Data.Semantic proximity Read ↗

RNA editing in the human ENCODE RNA-seq data.Semantic proximity Read ↗

High-Throughput Identification of Genetic Variation Impact on pre-mRNA Splicing EfficiencySemantic proximity Read ↗

Vex-seq: high-throughput identification of the impact of genetic variation on pre-mRNA splicing efficiency.Semantic proximity Read ↗

Genetic variation of pre-mRNA alternative splicing in human populations.Semantic proximity Read ↗

Genome-wide analysis of consistently RNA edited sites in human blood reveals interactions with mRNA processing genes and suggests correlations with cell types and biological variablesSemantic proximity Read ↗

Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals.Semantic proximity Read ↗

Pervasive noise in human splice site selectionSemantic proximity Read ↗

Genetic regulation of nascent RNA maturation revealed by direct RNA nanopore sequencing.Semantic proximity Read ↗

Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.