Association of the I148M/PNPLA3 (rs738409) polymorphism with premature coronary artery disease, fatty liver, and insulin resistance in type 2 diabetic patients and healthy controls. The GEA study.

doi:10.1016/j.imbio.2016.08.008

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Association of the I148M/PNPLA3 (rs738409) polymorphism with premature coronary artery disease, fatty liver, and insulin resistance in type 2 diabetic patients and healthy controls. The GEA study.

Immunobiology - 1 Oct 2017

Posadas-Sánchez Rosalinda, López-Uribe Ángel René, Posadas-Romero Carlos, Pérez-Hernández Nonanzit, Rodríguez-Pérez José Manuel, Ocampo-Arcos Wendy Angélica, Fragoso José Manuel, Cardoso-Saldaña Guillermo, Vargas-Alarcón Gilberto

Abstract excerpt

The aim of this study was to evaluate the potential use of the I148M/PNPLA3 (rs738409) gene polymorphism as a susceptibility marker for premature coronary artery disease (pCAD) and/or cardiovascular risk factors in Mexican type 2 diabetes mellitus patients (T2DM). The polymorphism was genotyped by 5' exonuclease TaqMan assays in a group of 2572 subjects (1103 with pCAD and 1469 healthy controls) belonging to the...

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PMID: 27615511
DOI: 10.1016/j.imbio.2016.08.008

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PNPLA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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