Isoleucine-to-methionine substitution at residue 148 variant of PNPLA3 gene and metabolic outcomes in gestational diabetes.

doi:10.3945/ajcn.114.095125

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Article

Isoleucine-to-methionine substitution at residue 148 variant of PNPLA3 gene and metabolic outcomes in gestational diabetes.

The American journal of clinical nutrition - 1 Feb 2015

Bo Simona, Gambino Roberto, Menato Guido, Canil Stefania, Ponzo Valentina, Pinach Silvia, Durazzo Marilena, Ghigo Ezio, Cassader Maurizio, Musso Giovanni

Abstract excerpt

BACKGROUND: A single nucleotide polymorphism (SNP) of the patatin-like phospholipase-3 (PNPLA3)/adiponutrin gene (rs738409 C>G) is strongly associated with nonalcoholic fatty liver disease; to our knowledge, no data are available on the impact of this PNPLA3 SNP on liver and metabolic outcomes du...

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Identifiers

PMID: 25646328
DOI: 10.3945/ajcn.114.095125

Genes

PNPLA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25646328-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Isoleucine-to-methionine substitution at residue 148 variant of PNPLA3 gene and metabolic outcomes in gestational diabetes.PMID 25646328Read ↗

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