Article
Arginine methylation promotes translation repression activity of eIF4G-binding protein, Scd6.
Nucleic acids research - 2 Nov 2016
Poornima Gopalakrishna, Shah Shanaya, Vignesh Venkadasubramanian, Parker Roy, Rajyaguru Purusharth I
Abstract excerpt
Regulation of translation plays a critical role in determining mRNA fate. A new role was recently reported for a subset of RGG-motif proteins in repressing translation initiation by binding eIF4G1. However the signaling mechanism(s) that leads to spatial and temporal regulation of repression activity of RGG-motif proteins remains unknown. Here we report the role of arginine methylation in regulation of repression...
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