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Article

The E2 ubiquitin conjugase Rad6 is required for the ArgR/Mcm1 repression of ARG1 transcription.

Molecular and cellular biology - 1 Jun 2002

Turner Suzanne D, Ricci Andrea R, Petropoulos Helen, Genereaux Julie, Skerjanc Ilona S, Brandl Christopher J

Abstract excerpt

Transcription of the Saccharomyces cerevisiae ARG1 gene is under the control of both positive and negative elements. Activation of the gene in minimal medium is induced by Gcn4. Repression occurs in the presence of arginine and requires the ArgR/Mcm1 complex that binds to two upstream arginine control (ARC) elements. With the recent finding that the E2 ubiquitin conjugase Rad6 modifies histone H2B, we examined...

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Source

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Identifiers

PMID: 12024015
DOI: 10.1128/MCB.22.12.4011-4019.2002
PMCID: PMC133851

Genes

ARG1
ARC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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