Article
ArgRII, a component of the ArgR-Mcm1 complex involved in the control of arginine metabolism in Saccharomyces cerevisiae, is the sensor of arginine.
Molecular and cellular biology - 1 Mar 2000
Amar N, Messenguy F, El Bakkoury M, Dubois E
Abstract excerpt
Repression of arginine anabolic genes and induction of arginine catabolic genes are mediated by a three-component protein complex, interacting with specific DNA sequences in the presence of arginine. Although ArgRI and Mcm1, two MADS-box proteins, and ArgRII, a zinc cluster protein, contain putative DNA binding domains, alone they are unable to bind the arginine boxes in vitro. Using purified glutathione...
Topics
- Amino Acid Sequence
- Arginine
- Base Sequence
- Binding Sites
- DNA-Binding Proteins
- Fungal Proteins
- Minichromosome Maintenance 1 Protein
- Molecular Sequence Data
- Mutation
- Repressor Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Alignment