Article
Detection of multiple mutations in urinary exfoliated cells from male bladder cancer patients at diagnosis and during follow-up.
Oncotarget - 11 Oct 2016
Critelli Rossana, Fasanelli Francesca, Oderda Marco, Polidoro Silvia, Assumma Manuela Bianca, Viberti Clara, Preto Mirko, Gontero Paolo, Cucchiarale Giuseppina, Lurkin Irene, Zwarthoff Ellen C, Vineis Paolo, Sacerdote Carlotta, Matullo Giuseppe, Naccarati Alessio
Abstract excerpt
Most bladder cancer (BC) patients need life-long, invasive and expensive monitoring and treatment, making it a serious burden on the health system. Thus, there is a pressing need for an accurate test to assist diagnosis and surveillance of BC as an alternative to cystoscopy. Mutations in human TERT, FGFR3, PIK3CA, and RAS genes have been proposed as potential molecular markers in bladder tumor. Their concomitant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.