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Detection of bladder cancer using urinary cell‐free DNA and cellular DNA

1 Jan 2020

Abstract excerpt

BACKGROUND: The present study sought to identify a panel of DNA markers for noninvasive diagnosis using cell-free DNA (cfDNA) from urine supernatant or cellular DNA from urine sediments of hematuria patients. A panel of 48 bladder cancer-specific genes was selected. A next-generation sequencing-based assay with a cfDNA barcode-enabled single-molecule test was employed. Mutation profiles of blood, urine, and tumor...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 31938901
DOI: 10.1186/s40169-020-0257-2

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