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Article

Potentially functional genetic variants in microRNA processing genes and risk of HBV-related hepatocellular carcinoma.

Molecular carcinogenesis - 1 Nov 2013

Liu Li, An Jiaze, Liu Jibin, Wen Juan, Zhai Xiangjun, Liu Yao, Pan Shandong, Jiang Jie, Wen Yang, Liu Zheng, Zhang Yixin, Chen Jianguo, Xing Jinliang, Ji Guozhong, Shen Hongbing, Hu Zhibin, Fan Zhining

Abstract excerpt

Genetic variations in miRNA processing genes may affect the biogenesis of miRNA, hence risk of HBV infection and hepatocellular carcinoma (HCC) development. In the present study, we hypothesized that potentially functional polymorphisms in 3'-untranslated region (UTR) of miRNA processing genes might contribute to susceptibility of HBV infection and HCC development. To test the hypothesis, we genotyped three...

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Identifiers

PMID: 23868705
DOI: 10.1002/mc.22062

Genes

RAN
DICER1
PIWIL1

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