Article
SDF1 Polymorphisms Influence Outcome in Patients with Symptomatic Cardiovascular Disease.
PloS one - 1 Jan 2016
Rath Dominik, Schaeffeler Elke, Winter Stefan, Hewer Jens, Müller Karin, Droppa Michal, Stimpfle Fabian, Gawaz Meinrad, Schwab Matthias, Geisler Tobias
Abstract excerpt
BACKGROUND: SDF1 and its cognate receptors CXCR4 and CXCR7 are involved in myocardial repair and are associated with outcome in cardiovascular patients. Hence, we aimed to investigate clinically significant SDF1 SNPs for their prognostic impact in patients with cardiovascular disease. METHODS AND RESULTS: Genotyping for selected SDF1 variants (rs1065297, rs2839693, rs1801157, rs266087, rs266085 and was...
