Article
Vascular endothelial growth factor-A promoter polymorphisms, circulating VEGF-A and survival in acute coronary syndromes.
PloS one - 1 Jan 2021
Palmer Barry R, Paterson Melinda A, Frampton Chris M, Pilbrow Anna P, Skelton Lorraine, Pemberton Chris J, Doughty Robert N, Ellis Chris J, Troughton Richard W, Richards A Mark, Cameron Vicky A
Abstract excerpt
BACKGROUND: Development of a competent collateral circulation in established coronary artery disease is cardio-protective. The vascular endothelial growth factor (VEGF) system plays a key role in this process. We investigated the prognostic performance of circulating VEGF-A and three genetic variants in the VEGFA gene in a clinical coronary cohort. METHODS AND RESULTS: The Coronary Disease Cohort Study (CDCS)...
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